2021 Ford F150 5.0 performance issues

[GAPDFN5.0]

21 Ford F150 STX 5.0 issues.
So I?m new here and I really need help resolving an issue with my F150. Heres what I got:

2021 Ford F150, with headers, full catback exhaust, cold air and 93 e85 flex/race tune. Driving on 93, truck died, put some 87 octane in it that I had, wouldnt crank, codes showed number 6 cyclinder misfiring, brand new plugs, dies going below 2000-3000 rpms, honestly runs like complete sh*t now the fuel light has been on and wont go off, truck sounds and performs like complete garbage. I can crank it, put in drive and go and it won?t die. If i let it idle dies within 10-15s. Don?t hear any knocking or any sounds

I was thinking fuel system but Im not expert by any means, so any reply helps!

Thanks in advance!

[engineermike]

Data log? Codes?

[GAPDFN5.0]

Codes:
C0604
P0306
307
313
430
6A0
P3442
P3450
I don?t currently have data logs. I?m not home at the moment.

[engineermike]

Sounds like some DoD problem. May not be tune related.

[GAPDFN5.0]

Ok, is there any information on a fix? or just any information to give in general

[GAPDFN5.0]

Also could the tune have detected the 87 and mess the tune up or deactivate it?

[engineermike]

Assuming your tuner didn’t mess it up, a good f150 flex tune will learn octane and alcohol%. None of this learning will cause missing cylinders and codes thrown.

[GAPDFN5.0]

Ok, do you have any information on a solution to the DoD problem?