Yes tuning in closed loop is just fine. I think everyone is getting off track here and forgetting the OPs issue. clearly injector settings need some attention.
I would not make ANY changes to the VE table until these are sorted out. Yes, Yes, Yes you can tune just fine in closed loop but you are having other issues. Stop recommending that the OP make changes using "trim tuning" to the VE table.... his first major issue with injector settings needs to be resolved. I still recommend a short drive and log with forced open loop to see how it runs. His trims are shooting hard negative because closed loop is unable to make PW changes under low map conditions... something I have dealt with recently and the fix is actually through injector settings, not by adjusting the VE using short term trims. Trims work by using PW changes.... if they cant do that because PW is bottomed out then there is no point in scaling the VE table down. you need to figure this out first.
to Tictack - your narrowbands look as though they are operating normally. your issue is with injector settings and bottoming out at idle because your injectors are fairly large. Force open loop using closed loop enable ETC or via the scanner and see if your idle injector PW drops from 1.8. just try it.