Back in the day before widebands were available to kids, I was playing with V8 supercharged (small blowers) and the way we did it back then was by plug reading mostly.
I would take my 60's era V8 smallblock with 10psi of roots-blower boost using a 'blower carb' , run it hard then shut it down and check the plugs,
adjust carb jets and repeat the cycle.
It is possible but with the availability of widebands, plug reading has become more for checking ignition timing and engine health, rather than engine fuel related.
Just mention all this because, it would be a good idea to research up on plug reading, distributor weight advance models, old tech to get your knowledge from how things used to be done, because thats sort of like a foundation for the more advanced topics.