it should be easy to rescale things for boost in the VE tables and fuel tables, the main tables work off Pressure Ratio, which is MAP/Baro. All the table axes can be edited in that regard, they are not fixed. The MAP sensor calibration can also be edited no problems.
You just never know what might require a custom OS, personally i hope it won't but you never know. Sometimes things get overlooked if the designer knows this controller will only ever be used on a NA engine.
Although the SRT4 and v8's share most of the same code, the turbo code is not compiled into the V8's so you can't actually just turn any of it on because it's not there (unlike GM).